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    A Computable General Equilibrium (CGE) model in a bottom-up approach - based on microfoundations - and a Social Accounting Matrix (SAM) for the regional economy of Chiapas are built. Methodology: This research applies a Computable General Equilibrium (CGE) model. It is a system of equations that describes an entire economy and all the interactions between productive sectors, commodity and factor markets, and institutions. All of the equations are solved simultaneously to find an economy-wide equilibrium in which demand and supply quantities are equal in every market at a certain level of prices (Burfisher, 2011). Two of the features of this model are that, on one hand, it implements a “bottom-up” approach, that is, it is focused on individual markets and economic agents. On the other hand, it is partially synthetic. In other words, most parameters can be calibrated with data from the SAM. Data framework: A Social Accounting Matrix (SAM) is a balanced square matrix that represents all income and expenditure flows between productive sectors, markets, and economic agents of an economy at a given period of time (Müller, Perez & Hubertus, 2009). It is based on the double entry bookkeeping in accounting, which requires that total revenue equals total expenditure in each single account included in the SAM (Breisinger, Thomas & Thurlow, 2010). The main features of the Chiapas SAM are that production activities are broken down in 10 sectors, according to the North American Industry Classification System (NAICS). There is one commodity per economic activity. Factors of production are disaggregated into formal and informal labor, and capital. Direct taxes are broken up into activity tax, social security contributions, household and corporate income taxes, ‘tenencia’ tax (ownership tax, i.e. a tax associated with the possession or use of vehicles), and regional payroll tax (‘nomina’). Indirect taxes, in turn, are value-added, sales and export taxes, and import tariffs. Subsidies on production by economic activity are also included. Households are disaggregated by income quintiles. Social transfers are split in non-conditional (Procampo, universal pension, PAL-Sin Hambre , temporary employment program, and the regional program Amanecer ) and Oportunidades. The latter is also broken down into its five components: food, elderly, education, child, and energy. The introduction of conditional cash transfers in the SAM is particularly relevant because it allows assessing the impact of changes in their amount and distribution on household income, poverty reduction, income inequality, and economic growth at the regional level. Data sources: - National Institute of Statistics and Geography (INEGI): 2012 National Employment and Occupation Survey 2013 Chiapas Statistical Yearbook 2012 National Household Income-Expenditure Survey 2012 Chiapas Statistical Perspective 2003-2012 Goods and Services Accounts (SCNM) 2003-2012 Institutional Sector Accounts (SCNM) 2008 Input-Output Table 2008 Supply and Use Tables - Chiapas State Committee of Statistical and Geographical Information (CEIEG): 2012 Chiapas Employment and Occupation Survey 2012 Chiapas Monthly Statistical Reports of IMSS-insured Workers - Federal Ministry of Labor and Social Welfare (STYPS): 2012 IMSS-registered Daily Salary by Economic Activity 2012 IMSS-insured Workers